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Acido Folico (Vitamina B9) 400 mcg, 250 Tablets [#1403]

012820_A
Holland & Barrett Raspberry Ketones Energy Formula 120 Capsules
Prezzo di vendita14,99 €
Sconto
Ammontare IVA
Disponibile
È noto che l'acido folico è importante per le donne in gravidanza, ma sapevi anche che questa vitamina B essenziale supporta anche la salute cardiovascolare nelle donne e negli uomini? L'acido folico fa parte di una triade di vitamine del gruppo B - insieme alle vitamine B-6 e B-12 - che aiuta a promuovere la salute del cuore.
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Overview Information

Folate and folic acid are forms of a water-soluble B vitamin. Folate occurs naturally in food, and folic acid is the synthetic form of this vitamin. Since 1998, folic acid has been added to cold cereals, flour, breads, pasta, bakery items, cookies, and crackers, as required by federal law. Foods that are naturally high in folate include leafy vegetables (such as spinach, broccoli, and lettuce), okra, asparagus, fruits (such as bananas, melons, and lemons) beans, yeast, mushrooms, meat (such as beef liver and kidney), orange juice, and tomato juice.

Folic acid is used for preventing and treating low blood levels of folate (folate deficiency).

Women who are pregnant or might become pregnant take folic acid to prevent miscarriage and "neural tube defects." Birth defects that occur due to folate deficiency such as spina bifida, when the fetal spine and back do not close during development. Folic acid is also tried for many other conditions including nerve pain in diabetes, heart disease, dementia, and many others.

Folic acid is often used in combination with other B vitamins.

How does it work?

Folic acid is needed for the proper development of the human body. It is involved in producing the genetic material called DNA and in numerous other bodily functions.

Uses & Effectiveness

Folate deficiency: Taking folic acid improves folate deficiency.
Gum disease in women who are pregnant: Applying folic acid to the gums seems to improve gum disease during pregnancy.
Serious kidney disease (end-stage renal disease or ESRD): About 85% of people with serious kidney disease have high levels of homocysteine. High levels of homocysteine have been linked to heart disease and stroke. Taking folic acid lowers homocysteine levels in people with serious kidney disease. 
High amounts of homocysteine in the blood (hyperhomocysteinemia): High levels of homocysteine have been linked to heart disease and stroke. Taking folic acid lowers homocysteine levels by 20% to 30% in people with normal to slightly elevated homocysteine levels. It is recommended that people with homocysteine levels greater than 11 micromoles/L supplement with folic acid and vitamin B12.
Toxicity caused by the drug methotrexate: Taking folic acid seems to reduce nausea and vomiting, which are possible side effects of methotrexate treatment.
Birth defects of the brain and spine (neural tube birth defects): Folic acid during pregnancy reduces the risk of neural tube birth defects. It is recommended that pregnant women get 600-800 mcg of folic acid per day from their diet or supplements starting 1 month before pregnancy and during pregnancy. Pregnant women with a history of neural tube birth defects are advised to get 4000 mcg of folic acid per day.
An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD): Research shows that taking folic acid with other vitamins including vitamin B6 and vitamin B12 reduces the risk of developing age-related vision loss.
Depression: Limited research shows that taking folic acid along with antidepressants seems to improve symptoms in people with depression.
High blood pressure: Research shows that taking folic acid daily for at least 6 weeks reduces blood pressure in people with high blood pressure. But Taking folic acid with blood pressure medication does not seem to lower blood pressure more than taking only blood pressure medicine.
A skin disorder that causes white patches to develop on the skin (vitiligo): Taking folic acid by mouth seems to improve symptoms of vitiligo.
 

Side Effects & Safety

When taken by mouth: Folic acid is LIKELY SAFE for most people when taken by mouth. Most adults do not experience any side effects when used in doses less than 1 mg daily.

Folic acid is POSSIBLY UNSAFE when taken by mouth in large doses, long-term. Although doses up to 5 mg daily have been safely used in some research, doses of folic acid greater than 1 mg daily might cause abdominal cramps, diarrhea, rash, sleep disorders, irritability, confusion, nausea, stomach upset, behavior changes, skin reactions, seizures, gas, excitability, and other side effects.

There is also some concern that taking too much folic acid for a long period of time might cause serious side effects. Some research suggests that taking folic acid in doses of 800 mcg to 1.2 mg daily might increase the risk of heart attack in people who have heart problems. Other research suggests that taking these high doses might also increase the risk of cancer such as lung or prostate cancer.

When given as a shot: Folic acid is LIKELY SAFE for most people when injected into the body. Most adults do not experience any side effects when used in doses less than 1 mg daily.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Folic acid is LIKELY SAFE when taken by mouth appropriately during pregnancy and breast-feeing. Taking 300-400 mcg of folic acid daily is commonly used during pregnancy to prevent birth defects.

Procedures to widen narrowed arteries (angioplasty): Using folic acid, vitamin B6, and vitamin B12 intravenously (by IV) or by mouth might worsen narrowed arteries. Folic acid should not be used by people recovering from this procedure.

Cancer: Early research suggests that taking 800 mcg to 1 mg of folic acid daily might increase the risk of cancer. Until more is known, people with a history of cancer should avoid high doses of folic acid.

Heart disease: Early research suggests that taking folic acid plus vitamin B6 might increase the risk for heart attack in people with a history of heart disease.

Malaria: Early research suggests that taking folic acid plus iron might increase the risk of death or need for treatment in hospital in areas of the world where malaria is common.

Anemia caused by vitamin B12 deficiency: Taking folic acid might mask anemia caused by vitamin B12 deficiency and delay appropriate treatment.

Seizure disorder: Taking folic acid supplements might make seizures worse in people with seizure disorders, particularly in high doses.

Interactions

.Moderate Interaction

Be cautious with this combination:

Fosphenytoin (Cerebyx) interacts with FOLIC ACID

Fosphenytoin (Cerebyx) is used for seizures. The body breaks down fosphenytoin (Cerebyx) to get rid of it. Folic acid can increase how quickly the body breaks down fosphenytoin (Cerebyx). Taking folic acid along with fosphenytoin (Cerebyx) might decrease the effectiveness of fosphenytoin (Cerebyx) for preventing seizures.

Methotrexate (MTX, Rheumatrex) interacts with FOLIC ACID

Methotrexate (MTX, Rheumatrex) works by decreasing the effects of folic acid in the body's cells. Taking folic acid pills along with methotrexate might decrease the effectiveness of methotrexate (MTX, Rheumatrex).

Phenobarbital (Luminal) interacts with FOLIC ACID

Phenobarbital (Luminal) is used for seizures. Taking folic acid can decrease how well phenobarbital (Luminal) works for preventing seizures.

Phenytoin (Dilantin) interacts with FOLIC ACID

The body breaks down phenytoin (Dilantin) to get rid of it. Folic acid might increase how quickly the body breaks down phenytoin (Dilantin). Taking folic acid and taking phenytoin (Dilantin) might decrease the effectiveness of phenytoin (Dilantin) and increase the possibility of seizures.

  • Primidone (Mysoline) interacts with FOLIC ACID

    Primidone (Mysoline) is used for seizures. Folic acid might cause seizure in some people. Taking folic acid can along with primidone (Mysoline) might decrease how well primidone works for preventing seizures.

  • Pyrimethamine (Daraprim) interacts with FOLIC ACID

    Pyrimethamine (Daraprim) is used to treat parasite infections. Folic acid might decrease the effectiveness of pyrimethamine (Daraprim) for treating parasite infections.

  • Dosing

    The following doses have been studied in scientific research:

    ADULTS

    BY MOUTH:

    • For folic acid deficiency: the typical dose is 250 mcg (micrograms) to 1 mg (milligrams) per day.
    • For preventing birth defects of the brain and spine (neural tube birth defects): Women capable of becoming pregnant should take 400 mcg of folic acid per day from fortified foods or supplements. Women who are pregnant are advised to take 600 mcg of folic acid per day from fortified foods or supplements. Women with a history of previous pregnancy complicated by neural tube defects usually take 4 mg per day beginning one month before and continuing for up to 3 months after conception.
    • For reducing colon cancer risk: 400 mcg per day.
    • For treating high amounts of homocysteine in the blood (hyperhomocysteinemia):
      • 200 mcg to 15 mg per day has been used, although daily doses of 800 mcg to 1 mg appear to be most effective.
      • In people with end-stage renal disease, high homocysteine levels may be more difficult to treat, and doses of 800 mcg to 40 mg per day have been used. Other dosage plans such as 2.5-5 mg three times weekly have also been used. Doses higher than 15 mg daily do not seem to be more effective than lower doses.
    • For improving the response to medications for depression: 200-500 mcg daily has been used.
    • For a skin disorder that causes white patches to develop on the skin (vitiligo): 5 mg is typically taken twice daily.
    • For reduction of toxicity caused by the drug methotrexate: 1 mg per day is probably enough, but up to 5 mg per day may be used.
    • For preventing an eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD): 2.5 mg of folic acid, 1 mg of vitamin B12 (cyanocobalamin), and 50 mg of vitamin B6 (pyridoxine) per day have been used.
    • For preventing stroke. 500 mcg to 40 mg of folic acid per day have been used. The greatest benefit seems to occur with folic acid doses of 800 mcg per day or lower.
    APPLIED TO THE SKIN:
    • For gum disease in women who are pregnant: a mouthwash containing folic acid has been used twice daily for one minute.
    GIVEN BY NEEDLE:
    • For homocysteine lowering in people with end-stage renal disease (ESRD): 10 mg post-hemodialysis three times per week has been given in the vein.
  • CHILDREN

    BY MOUTH:

    • For gum enlargement caused by the drug phenytoin (6-15 years): folic acid 500 mcg daily has been used.

    The adequate intakes (AI) for infants are 65 mcg for infants 0-6 months and 80 mcg for infants 7-12 months of age. The recommended dietary allowances (RDAs) for folate in DFE, including both food folate and folic acid from fortified foods and supplements are: Children 1-3 years, 150 mcg; Children 4-8 years, 200 mcg; Children 9-13 years, 300 mcg; Adults over 13 years, 400 mcg; Pregnant women 600 mcg; and breast-feeding women, 500 mcg. The tolerable upper intake levels (UL) of folate are 300 mcg for children 1-3 years of age, 400 mcg for children 4-8 years, 600 mcg for children 9-13 years, 800 mcg for adolescents 14-18 years, and 1 mg for everyone over 18 years of age.
Indicazioni

IT: Per gli adulti, assumere una (1) compressa fino a due (2) volte al giorno, preferibilmente durante i pasti.

EN:  For adults, take one (1) tablet up to two (2) times daily, preferably with meals.

Ingredienti

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Other Ingredients: Vegetable Cellulose, Calcium Carbonate. Contains <2% of: Silica, Vegetable Magnesium Stearate.

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish, Sodium Free.

Avvertenze

IT: In caso di gravidanza, allattamento, assunzione di farmaci o condizioni mediche, consultare il medico prima dell'uso. Interrompere l'uso e consultare il medico se si verificano reazioni avverse. Tenere fuori dalla portata dei bambini. Conservare a temperatura ambiente. Non utilizzare se il sigillo sotto il cappuccio è rotto o mancante.

EN: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Keep out of reach of children. Store at room temperature. Do not use if seal under cap is broken or missing.

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