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When taken by mouth: Folic acid is LIKELY SAFE for most people when taken by mouth. Most adults do not experience any side effects when used in doses less than 1 mg daily.
Folic acid is POSSIBLY UNSAFE when taken by mouth in large doses, long-term. Although doses up to 5 mg daily have been safely used in some research, doses of folic acid greater than 1 mg daily might cause abdominal cramps, diarrhea, rash, sleep disorders, irritability, confusion, nausea, stomach upset, behavior changes, skin reactions, seizures, gas, excitability, and other side effects.
There is also some concern that taking too much folic acid for a long period of time might cause serious side effects. Some research suggests that taking folic acid in doses of 800 mcg to 1.2 mg daily might increase the risk of heart attack in people who have heart problems. Other research suggests that taking these high doses might also increase the risk of cancer such as lung or prostate cancer.
When given as a shot: Folic acid is LIKELY SAFE for most people when injected into the body. Most adults do not experience any side effects when used in doses less than 1 mg daily.
Pregnancy and breast-feeding: Folic acid is LIKELY SAFE when taken by mouth appropriately during pregnancy and breast-feeing. Taking 300-400 mcg of folic acid daily is commonly used during pregnancy to prevent birth defects.
Procedures to widen narrowed arteries (angioplasty): Using folic acid, vitamin B6, and vitamin B12 intravenously (by IV) or by mouth might worsen narrowed arteries. Folic acid should not be used by people recovering from this procedure.
Cancer: Early research suggests that taking 800 mcg to 1 mg of folic acid daily might increase the risk of cancer. Until more is known, people with a history of cancer should avoid high doses of folic acid.
Heart disease: Early research suggests that taking folic acid plus vitamin B6 might increase the risk for heart attack in people with a history of heart disease.
Malaria: Early research suggests that taking folic acid plus iron might increase the risk of death or need for treatment in hospital in areas of the world where malaria is common.
Anemia caused by vitamin B12 deficiency: Taking folic acid might mask anemia caused by vitamin B12 deficiency and delay appropriate treatment.
Seizure disorder: Taking folic acid supplements might make seizures worse in people with seizure disorders, particularly in high doses.
.Moderate Interaction
Be cautious with this combination:
Fosphenytoin (Cerebyx) interacts with FOLIC ACID
Fosphenytoin (Cerebyx) is used for seizures. The body breaks down fosphenytoin (Cerebyx) to get rid of it. Folic acid can increase how quickly the body breaks down fosphenytoin (Cerebyx). Taking folic acid along with fosphenytoin (Cerebyx) might decrease the effectiveness of fosphenytoin (Cerebyx) for preventing seizures.
Methotrexate (MTX, Rheumatrex) interacts with FOLIC ACID
Methotrexate (MTX, Rheumatrex) works by decreasing the effects of folic acid in the body's cells. Taking folic acid pills along with methotrexate might decrease the effectiveness of methotrexate (MTX, Rheumatrex).
Phenobarbital (Luminal) interacts with FOLIC ACID
Phenobarbital (Luminal) is used for seizures. Taking folic acid can decrease how well phenobarbital (Luminal) works for preventing seizures.
Phenytoin (Dilantin) interacts with FOLIC ACID
The body breaks down phenytoin (Dilantin) to get rid of it. Folic acid might increase how quickly the body breaks down phenytoin (Dilantin). Taking folic acid and taking phenytoin (Dilantin) might decrease the effectiveness of phenytoin (Dilantin) and increase the possibility of seizures.
Primidone (Mysoline) interacts with FOLIC ACID
Primidone (Mysoline) is used for seizures. Folic acid might cause seizure in some people. Taking folic acid can along with primidone (Mysoline) might decrease how well primidone works for preventing seizures.
Pyrimethamine (Daraprim) interacts with FOLIC ACID
Pyrimethamine (Daraprim) is used to treat parasite infections. Folic acid might decrease the effectiveness of pyrimethamine (Daraprim) for treating parasite infections.
The following doses have been studied in scientific research:
ADULTS
BY MOUTH:
BY MOUTH:
IT: Per gli adulti, assumere una (1) compressa fino a due (2) volte al giorno, preferibilmente durante i pasti.
EN: For adults, take one (1) tablet up to two (2) times daily, preferably with meals.
Other Ingredients: Vegetable Cellulose, Calcium Carbonate. Contains <2% of: Silica, Vegetable Magnesium Stearate.
No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish, Sodium Free.
IT: In caso di gravidanza, allattamento, assunzione di farmaci o condizioni mediche, consultare il medico prima dell'uso. Interrompere l'uso e consultare il medico se si verificano reazioni avverse. Tenere fuori dalla portata dei bambini. Conservare a temperatura ambiente. Non utilizzare se il sigillo sotto il cappuccio è rotto o mancante.
EN: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Keep out of reach of children. Store at room temperature. Do not use if seal under cap is broken or missing.
Condividiamo le nostre scoperte mediche sull'efficacia del "mix di integratori alimentari" con le seguenti aziende farmaceutiche: